Unusual case (updated)
Friday, December 03 2010 @ 10:24 AM CST
Contributed by: Admin
Clnical Hx: 42 year old man with chronic back pain.
This is 42 yo man with a chronic back pain for some time. He was found to have a paraspinal mass in the toracic region abuting the lung. He is smoker but otherwise heathy.
The mass is not cleary visualized on CT-scans with no contrast.
Im showing the core biopsies Here
Be shure to upgrade your Microsoft Silverlight plugin.
I need some differential diagnosis or additional immunostains. So far this neoplasm is postive for CK-7 and Vimentin.
Negative for: CK-20, TTF-1, p63, S-100 and CD34
Additional stains that will be coming up: RCC, CD10, CD99, BCL-2, Calretinin and p53 . I am after sarcomatoid RCC, Synovial sarcoma and not-likely Mesothelioma.
Thanx for the help. You can comment below .
Additional stains: RCC -, CD10-, CD99-, BCL-2-, p53 focall positiveity, CAM5.2 positive.
FINAL DIAGNOSIS : HIGH GRADE SARCOMA (EPITHELIOID AND SCLEROSING FIBROSARCOMA OR LIPOSARCOMA VARIANT)
as per consulation with Dr. J. Rosai.