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Wednesday, June 19 2013 @ 03:06 AM CDT

Unusual case (updated)

Clnical Hx: 42 year old man with chronic back pain.


This is 42  yo man with a chronic back pain for some time. He was found to have a paraspinal mass in the toracic region abuting the lung. He is smoker but otherwise heathy.

The mass is not cleary visualized on CT-scans with no contrast.

Im showing the core biopsies Here

Be shure to upgrade your Microsoft Silverlight plugin.

I need some differential diagnosis or additional immunostains. So far this neoplasm is postive for CK-7 and Vimentin.

Negative for: CK-20, TTF-1, p63, S-100 and CD34

Additional stains that will be coming up: RCC, CD10, CD99, BCL-2, Calretinin and p53 . I am after sarcomatoid RCC, Synovial sarcoma and not-likely Mesothelioma.

Thanx for the help. You can comment below .

 Additional stains: RCC -, CD10-, CD99-, BCL-2-, p53 focall positiveity, CAM5.2 positive.

FINAL DIAGNOSIS : HIGH GRADE SARCOMA (EPITHELIOID AND SCLEROSING FIBROSARCOMA OR LIPOSARCOMA VARIANT)

as per consulation with Dr. J. Rosai.

 

 

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