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Thursday, September 09 2010 @ 11:18 PM CDT

Urologic Pathology
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The lesion consists of multiple locules, variable in size, each lined by epithelium, and the entire mass circumscribed by a thick capsule. The stroma is quite cellular in some areas and, unlike dysgenesis, contains no glomeruli.
Cystic Nephroma
Tuesday, December 01 2009 @ 12:19 PM CST
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The typical Wilms' tumor consists of three elements, all seen on this slide: epithelial, stromal and undifferentiated. The darkly staining, intensely cellular areas are the undifferentiated nephrogenic component. In places, these appear to differentiate into tubules, occasionally glomeruloid structures all lined by neoplastic cells. The above structures are contained in a spindle cell stroma.
Wilms Tumor
Tuesday, December 01 2009 @ 12:19 PM CST
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The lesion is very pleomorphic with numerous mitotic figures. Three distinct cell types may be identified: very small ones with round, pyknotic nuclei and pink cytoplasm, very large, sometimes bizarre, cells with either dark or vacuolated nuclei and a third predominant type, comparable in size to the cells of typical seminoma. The latter two-cell types often display a rather distinctive chromatin pattern which is filamentous spireme-like, rather than punctate, as in other seminomas.
Spermatocytic seminoma
Wednesday, November 18 2009 @ 08:25 AM CST
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Note the marked anaplasia of the cells, mitotic activity, hemorrhage and tumor necrosis.
Malignant Lydig cell tumor
Wednesday, November 18 2009 @ 08:25 AM CST
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There is a testis with seminiferous tubules lined mostly by Sertoli cells, and some of the lumina are calcified. A tumor is present in the tubules and consists of two elements: seminoma-like germ cells and Sertoli-granulosa cells arranged around pink, round masses resembling Call-Exner bodies. This combination of stromal and germ cell tumor constitutes gonadoblastoma. There is also marked Leydig cell proliferation.
Gonadoblastoma
Wednesday, November 18 2009 @ 08:25 AM CST
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Urothelial mucosa with moderate to marked anaplasia, failure of maturation from the base to the surface, condensation of nuclei and many mitotic figures in various levels of the epithelial layer.
Urothelial carcinoma in situ
Thursday, April 23 2009 @ 12:36 PM CDT
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The glands are approximately the size of other hyperplastic glands, the secretory cells have a normal appearance except that they are markedly increased in number and show cribriform bridging across the lumen or largely fill the lumen. This has been reported as "clear cell cribriform hyperplasia" although the cells are not water clear. This is distinguished from PIN by the absence of any nuclear atypia and from cribriform carcinoma by the presence of basal cells.
Cribriform Prostatic Glandular Hyperplasia
Thursday, April 23 2009 @ 11:57 AM CDT
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Grossly, adrenocortical carcinomas are often large, with a tan-yellow cut surface, and areas of hemorrhage and necrosis. On microscopic examination, the tumor usually displays sheets of atypical cells with some resemblance to the cells of the normal adrenal cortex. The presence of invasion and mitotic activity help differentiate small cancers from adrenocortical adenomas. There are several relatively rare variants of adrenal cortical carcinoma: Oncocytic adrenal cortical carcinoma, Myxoid adrenal cortical carcinoma, Carcinosarcoma, Adenosquamous adrenocortical carcinoma, Clear cell adrenal cortical carcinoma. Differential diagnosis includes: Adrenocortical adenoma, Renal cell carcinoma, Adrenal medullary tumors, Hepatocellular carcinoma.
Adrenal Cortical Carcinoma (Gross)
Monday, March 24 2008 @ 09:26 PM CDT
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Multilocular cystic renal tumor is characterized as a solitary, well-circumscribed, multiseptated mass of noncommunicating fluid-filled loculi that is surrounded by a thick fibrous capsule and compressed renal parenchyma. The mass is typically large. I
Multilocular Cystic Nephroma
Saturday, August 02 2008 @ 05:16 PM CDT
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The mixed epithelial and stromal tumor is a recently established tumor of the kidney of unknown etiology. MEST is previously reported under different names as 'Adult mesoblastic nephromas' 'Cystic hamartoma of renal pelvis' 'Cystic nephroma'. MEST has
Cystic Hamartoma of the Kidney
Saturday, August 02 2008 @ 05:16 PM CDT
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MA is well circumscribed lession composed of small uniform round acini and tubular sructures wtih scant stroma. The acini are lined by uniform, hiperchromatic cells with scant cytoplasm. There is no nuclear atypia, no mitoses and no necrosis.
Metanephric Adenoma
Saturday, August 02 2008 @ 05:16 PM CDT
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Rare entity which presents usually in adults as well circumscribed grossly cystic mass. At low power has a specific architecture: tubules with variable size separated by a thin delicate septa ("spider web"). On high power the septa a lined by low cuboidal
Tubulocystic Carcinoma of the Kidney
Saturday, August 02 2008 @ 05:16 PM CDT
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