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Dermatopathology
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A leiomyoma arising from vascular smooth muscle, usually occurring as a solitary nodular, sometimes painful, subcutaneous tumor on the lower extremity, more deeply situated than ordinary leiomyoma; usually seen in middle-aged women.
Angioleiomyoma
Saturday, August 02 2008 @ 05:19 PM CDT
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SK
Saturday, August 02 2008 @ 05:19 PM CDT
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SCC
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The overlying epidermis is usually acanthotic. Pseudoepitheliomatous hyperplasia and a basaloid proliferation may be noted. Increased pigment may be seen, which may be iron or melanin. Most lesions display a grenz zone of normal papillary dermis overlying
Dermatofibroma
Saturday, August 02 2008 @ 05:19 PM CDT
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In the plaque type of DFSP, slender tumor cells with large, spindle-shaped nuclei are embedded fairly uniformly in the collagen stroma, parallel to the skin surface. Mitotic figures are sparse. The more characteristic findings are seen in the nodular type
Dermatofibrosarcoma Protuberans
Saturday, August 02 2008 @ 05:19 PM CDT
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Glomus tumor is a rare and benign vascular tumor. The normal glomus unit is a neuromyoarterial apparatus that functions to regulate skin circulation.Glomus tumors are found at the dermal and subdermal junction and have a fibrous capsule. They are made of
Glomus Tumor (Solid Variant)
Saturday, August 02 2008 @ 05:19 PM CDT
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Thick intertwined dermal collagen bundles oriented along the vertical axis of the lesion are usually found in continuity with the underlying dermis. Elastic fibers are usually present but are thin. The epidermis may be acanthotic and hyperkeratotic. They
Acral Fibrokeratoma
Saturday, August 02 2008 @ 05:19 PM CDT
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MCT are compoused of small, round, basophilic cells arranged in sheets, rests, or trabeculae. The tumor originates in the dermis. The overlying epidermis is usually spared. As it advances, the tumor infiltrates into underlying subcutaneous fat, fascia, an
Merkel Cell Tumor
Saturday, August 02 2008 @ 05:19 PM CDT
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Pilomatricoma is an uncommon, harmless, skin lesion derived from hair matrix cells. It is also spelled ‘pilomatrixoma’, and sometimes known as ‘calcifying epithelioma of Malherbe’. This tumor is composed of the epithelial components of the most proximal (
Pilomatricoma
Saturday, August 02 2008 @ 05:19 PM CDT
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Cylindroma is a dermal tumor without attachment to the epidermis. The lesion is composed of numerous oval and polygonal nests molded into a jigsawlike pattern. Masses of epithelial cells are surrounded and penetrated by a hyaline sheath. Tumor islands a
Cylindroma
Saturday, August 02 2008 @ 05:19 PM CDT
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Fibroepithelioma of Pinkus was first described by Herman Pinkus in 1953 who termed it premalignant fibroepithelial tumor of the skin. Although FEP traditionally is considered to be an unusual variant of basal cell carcinoma, its indolent nature and often asymptomatic clinical presentation suggest that it may be best classified as a benign counterpart of BCC, such as a trichoblastoma. This concept was supported by a recent study, representing the largest case series of FEP to date, whereby the features of FEP were compared with those of conventional BCC by immunohistochemical staining.In particular, FEP expressed significantly less p53 oncogene and MIB-1 proliferative marker than the conventional BCC. Moreover, Merkel cells were found within the lesions of FEP similar to many benign follicular tumors, but were absent in the conventional BCC. Finally, FEP consistently displays no infiltration of the subcutis and has no known aggressive clinical course. 1. Pinkus H. Premalignant fibroepithelial tumors of skin. AMA Arch Derm Syphilol 1953. 67: 598-615. 2. Bowen AR, LeBoit, PE. Fibroepithelioma of pinkus is a fenestrated trichoblastoma. Am J Dermatopathol. 2005 Apr;27(2):149-54. 3. McNiff JM, Eisen RN, Glusac EJ. Immunohistochemical comparison of cutaneous lymphadenoma, trichoblastoma, and basal cell carcinoma: support for classification of lymphadenoma as a variant of trichoblastoma. J Cutan Pathol. 1999 Mar;26(3):119-24. 4. Schulz T, Hartschuh W. Merkel cells are absent in basal cell carcinomas but frequently found in trichoblastomas. An immunohistochemical study. J Cutan Pathol. 1997 Jan;24(1):14-24.
Fibroepithelioma of Pinkus
Saturday, August 02 2008 @ 05:19 PM CDT
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Human Papilloma Virus types 1,2,4,7 Note the koilocytic changes...
Verruca Vulgaris
Saturday, August 02 2008 @ 05:19 PM CDT
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