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| the following crirteria should be applied: Large cells with abundant granular eosinophilic cytoplasm, nucleus to cytoplasm ratio of 1:2 or more, nuclei round, large and vesicular and may have a prominent cherry red nucleolus with sharply defined cell borders Immuno: GCFDP-15 and Androgen receptor positive DDX: Oncocytic carcinoma - GCDFP-15 negative Hystiocytoid carcinoma- weakly eosinophilic cytoplasm and amphophilic cytoplasm Secretory carcinoma- dPAS positive for mucin, young age |
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Tuesday, February 01 2011 @ 09:29 AM CST Comments 8 Views 4844 |
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Large cells with abundant granular eosinophilic cytoplasm, nucleus to interstitial lung disease cytoplasm ratio of 1:2 or more, nuclei round, large and vesicular and may have a prominent cherry red nucleolus with sharply defined cell borders
Immuno: GCFDP-15 and Androgen receptor positive
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