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Monday, April 21 2014 @ 04:42 AM CDT
Breast
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the following crirteria should be applied: Large cells with abundant granular eosinophilic cytoplasm, nucleus to cytoplasm ratio of 1:2 or more, nuclei round, large and vesicular and may have a prominent cherry red nucleolus with sharply defined cell borders
Immuno: GCFDP-15 and Androgen receptor positive

DDX:
Oncocytic carcinoma - GCDFP-15 negative
Hystiocytoid carcinoma- weakly eosinophilic cytoplasm and amphophilic cytoplasm
Secretory carcinoma- dPAS positive for mucin, young age

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Tuesday, February 01 2011 @ 09:29 AM CST
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